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Mariko Kambe Selected Research

GD3 ganglioside (GD(3))

10/2019TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes.
1/2018Differential roles of gangliosides in malignant properties of melanomas.
3/2014UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.
1/2014Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas.
8/2010Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.

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Mariko Kambe Research Topics

Disease

7Melanoma (Melanoma, Malignant)
12/2021 - 08/2010
2Neoplasms (Cancer)
12/2021 - 08/2010
2Neutropenia
04/2014 - 04/2012
1autosomal recessive Spastic paraplegia 26
09/2022
1Hereditary Spastic Paraplegia
09/2022
1Rare Diseases (Rare Disease)
09/2022
1Febrile Neutropenia
04/2014
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2014
1Lung Neoplasms (Lung Cancer)
04/2014
1Nausea
04/2014
1Colorectal Neoplasms (Colorectal Cancer)
04/2012
1Anorexia
04/2012
1Diarrhea
04/2012
1Stomach Neoplasms (Stomach Cancer)
01/2010

Drug/Important Bio-Agent (IBA)

6GangliosidesIBA
09/2022 - 12/2011
5GD3 ganglioside (GD(3))IBA
10/2019 - 08/2010
2EnzymesIBA
12/2021 - 03/2014
2IntegrinsIBA
12/2021 - 08/2010
2Fluorouracil (Carac)FDA LinkGeneric
04/2012 - 01/2010
1GD2 gangliosideIBA
12/2021
1Docetaxel (Taxotere)FDA Link
04/2014
1Vinorelbine (Navelbine)FDA LinkGeneric
04/2014
1GemcitabineFDA Link
04/2014
1Carboplatin (JM8)FDA LinkGeneric
04/2014
1Paclitaxel (Taxol)FDA LinkGeneric
04/2014
1(N- acetylneuraminyl)- galactosylglucosylceramide N-acetylgalactosaminyltransferaseIBA
03/2014
1GlycosyltransferasesIBA
03/2014
1Messenger RNA (mRNA)IBA
03/2014
1CytokinesIBA
03/2014
1Interleukin-6 (Interleukin 6)IBA
03/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2014
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2014
1Irinotecan (Camptosar)FDA LinkGeneric
04/2012
1Neuraminidase (Sialidase)IBA
12/2011
1Complementary DNA (cDNA)IBA
12/2011
1GlycolipidsIBA
08/2010
1Cisplatin (Platino)FDA LinkGeneric
01/2010

Therapy/Procedure

1Drug Therapy (Chemotherapy)
04/2014
1Therapeutics
04/2012
1Intravenous Infusions
04/2012